Associação do papilomavírus humano com os tumores esofágicos e gástricos: revisão integrativa

Abstract

Introduction: The human papillomavirus (HPV) infection has potential for stratified epithelium and correlates with malignant squamous cell tumors, but its association with other types of tumors is not well understood. The participation of HPV in esophageal and gastric tumors has been studied by several research groups. Objectives: we intend to undertake, through an integrative review, the association of human papilloma virus with esophageal and gastric tumors. Methodology: an integrative review was conducted from February to April 2016 from the online databases: PUBMED, MEDLINE, LILACS, SCIELO, SCIENCE DIRECT. The selection of items was performed from the inclusion criteria; original articles published between 2009 to 2015, using the descriptors: "esophageal", "gastric cancer" and "Papillomavirus". Results: After searching the databases were initially found 212 articles of which left over 11 articles selected after analysis of established criteria. Conclusion: most of the studies did not show HPV relationship with gastric and esophageal tumors, but did not use a large number of samples which may have influenced. However, latest articles and used more precise molecular resources report the association of HPV with gastric and esophageal tumors.