EFEITOS DO EXERCÍCIO FÍSICO PARA OS INDIVÍDUOS COM ANEMIA FALCIFORME: UMA REVISÃO BIBLIOGRÁFICA

Abstract

Introduction: Sickle cell disease (SCD) is a genetic disease brought about by the substitution of glutamic acid for valine in the β-6 position of the β-globin chain gene. Objective: To conduct a systematic review of articles that examined the effects of exercise for individuals with sickle cell anemia. Methods: This is a systematic review on electronic databases Lilacs (Latin American and Caribbean Health Sciences), SciELO (Scientific Electronic Library Online) and Medline / PubMed (National Library of Medicine National Institutes of Health ) using the following keywords: "sickle cell anemia", "hemoglobin S", "exercise" and "physical activity", beyond the logical operator "and" for the combinations of terms. All search processes, selection and evaluation of the articles were performed by peers. Results: we identified 11 articles published between the years 2005 and 2015. The sample size of the studies ranged from 15 to 160 individuals. All studies used aerobic exercise interventions and submaximal intensities. Conclusion: We conclude there is a predominance of studies using aerobic exercise with submaximal intensities. In addition, no difference was found regarding the response to exercise among individuals with and without SCD.